1. Introduction to Epalrestat Tablets

Epalrestat is a key medication for treating diabetic neuropathy. Its active ingredient is sensitive to stomach acid, so enteric coating is essential to protect it and ensure it releases in the intestines for optimal absorption.

2. Why Enteric Coating Matters

The enteric coating serves three critical functions:

Drug Protection: Shields epalrestat from gastric acid, preserving its effectiveness.

Reduced Irritation: Prevents direct contact with the stomach lining.

Targeted Release: Ensures the drug dissolves only in the intestines’ neutral/alkaline environment.

3. The Coating Process

3.1 Preparation Before Coating

3.2 Key Steps in the Coating Process

Coating Material Preparation: Mix the enteric polymer, plasticizer, and colorant (if needed) with purified water to form a 10-15% solution.

Actual Coating Operation:

Load core tablets into the rotating drum (10-15 rpm).

Adjust the spray gun (15-20 cm from the tablet bed) and spray at 5-10 mL/min.

Maintain drum temperature at 40-45°C for real-time drying.

Repeat until the coating reaches the desired thickness (5-10% weight gain).

4. Why Jianpai’s Coating Machine Stands Out

Jianpai’s high-efficiency coating machine offers significant advantages:

Results and Video Display

Using Jianpai’s coating machine produced excellent results:

Weight increased by 10% (meets coating standards).

Loss rate decreased by 5%, significantly lower than the industry average.

Please watch our video to see the perfect coating of this type of tablets using Jianpai’s high-efficiency coating machine. The enteric-coated epalrestat tablets have been completed. The weight has increased by 10% and the loss has decreased by 5%.

5. Conclusion

The coating of enteric tablets demands precise control of equipment, materials, and parameters. Jianpai’s Coating Equipment simplifies this process, making it suitable for novices while improving product quality and production efficiency.