{"id":4539,"date":"2025-09-27T10:26:39","date_gmt":"2025-09-27T02:26:39","guid":{"rendered":"https:\/\/www.jianpaitech.com\/?post_type=blog&#038;p=4539"},"modified":"2025-09-27T11:44:07","modified_gmt":"2025-09-27T03:44:07","slug":"unveiling-the-coating-process-of-enteric-coated-epalrestat-tablets","status":"publish","type":"blog","link":"https:\/\/www.jianpaitech.com\/tr\/blog\/unveiling-the-coating-process-of-enteric-coated-epalrestat-tablets\/","title":{"rendered":"Enterik kapl\u0131 epalrestat tabletlerin kaplama i\u015fleminin a\u00e7\u0131klanmas\u0131"},"content":{"rendered":"<div id=\"ez-toc-container\" class=\"ez-toc-v2_0_76 counter-hierarchy ez-toc-counter ez-toc-grey ez-toc-container-direction\">\n<div class=\"ez-toc-title-container\">\n<p class=\"ez-toc-title\" style=\"cursor:inherit\">\u0130\u00e7indekiler<\/p>\n<span class=\"ez-toc-title-toggle\"><a href=\"#\" class=\"ez-toc-pull-right ez-toc-btn ez-toc-btn-xs ez-toc-btn-default ez-toc-toggle\" aria-label=\"\u0130\u00e7erik Tablosunu De\u011fi\u015ftir\"><span class=\"ez-toc-js-icon-con\"><span class=\"\"><span class=\"eztoc-hide\" style=\"display:none;\">Ge\u00e7i\u015f yapmak<\/span><span class=\"ez-toc-icon-toggle-span\"><svg style=\"fill: #999;color:#999\" xmlns=\"http:\/\/www.w3.org\/2000\/svg\" class=\"list-377408\" width=\"20px\" height=\"20px\" viewbox=\"0 0 24 24\" fill=\"none\"><path d=\"M6 6H4v2h2V6zm14 0H8v2h12V6zM4 11h2v2H4v-2zm16 0H8v2h12v-2zM4 16h2v2H4v-2zm16 0H8v2h12v-2z\" fill=\"currentColor\"><\/path><\/svg><svg style=\"fill: #999;color:#999\" class=\"arrow-unsorted-368013\" xmlns=\"http:\/\/www.w3.org\/2000\/svg\" width=\"10px\" height=\"10px\" viewbox=\"0 0 24 24\" version=\"1.2\" baseprofile=\"tiny\"><path d=\"M18.2 9.3l-6.2-6.3-6.2 6.3c-.2.2-.3.4-.3.7s.1.5.3.7c.2.2.4.3.7.3h11c.3 0 .5-.1.7-.3.2-.2.3-.5.3-.7s-.1-.5-.3-.7zM5.8 14.7l6.2 6.3 6.2-6.3c.2-.2.3-.5.3-.7s-.1-.5-.3-.7c-.2-.2-.4-.3-.7-.3h-11c-.3 0-.5.1-.7.3-.2.2-.3.5-.3.7s.1.5.3.7z\"\/><\/svg><\/span><\/span><\/span><\/a><\/span><\/div>\n<nav><ul class='ez-toc-list ez-toc-list-level-1' ><ul class='ez-toc-list-level-2' ><li class='ez-toc-heading-level-2'><a class=\"ez-toc-link ez-toc-heading-1\" href=\"https:\/\/www.jianpaitech.com\/tr\/blog\/unveiling-the-coating-process-of-enteric-coated-epalrestat-tablets\/#1_Introduction_to_Epalrestat_Tablets\" >1. Epalrestat tabletlerine giri\u015f<\/a><\/li><li class='ez-toc-page-1 ez-toc-heading-level-2'><a class=\"ez-toc-link ez-toc-heading-2\" href=\"https:\/\/www.jianpaitech.com\/tr\/blog\/unveiling-the-coating-process-of-enteric-coated-epalrestat-tablets\/#2_Why_Enteric_Coating_Matters\" >2. Enterik kaplama neden \u00f6nemlidir?<\/a><\/li><li class='ez-toc-page-1 ez-toc-heading-level-2'><a class=\"ez-toc-link ez-toc-heading-3\" href=\"https:\/\/www.jianpaitech.com\/tr\/blog\/unveiling-the-coating-process-of-enteric-coated-epalrestat-tablets\/#3_The_Coating_Process\" >3. Kaplama i\u015flemi<\/a><\/li><li class='ez-toc-page-1 ez-toc-heading-level-2'><a class=\"ez-toc-link ez-toc-heading-4\" href=\"https:\/\/www.jianpaitech.com\/tr\/blog\/unveiling-the-coating-process-of-enteric-coated-epalrestat-tablets\/#4_Why_Jianpais_Coating_Machine_Stands_Out\" >4. Jianpai\u2019nin Kaplama Makinesi Neden \u00d6ne \u00c7\u0131k\u0131yor?<\/a><\/li><\/ul><\/li><li class='ez-toc-page-1 ez-toc-heading-level-1'><a class=\"ez-toc-link ez-toc-heading-5\" href=\"https:\/\/www.jianpaitech.com\/tr\/blog\/unveiling-the-coating-process-of-enteric-coated-epalrestat-tablets\/#5_Conclusion\" >5. Sonu\u00e7<\/a><\/li><\/ul><\/nav><\/div>\n<h2><span class=\"ez-toc-section\" id=\"1_Introduction_to_Epalrestat_Tablets\"><\/span><strong><b>1. Epalrestat tabletlerine giri\u015f<\/b><\/strong><span class=\"ez-toc-section-end\"><\/span><\/h2>\n<p>Epalrestat, diyabetik n\u00f6ropatiyi tedavi etmek i\u00e7in \u00f6nemli bir ila\u00e7t\u0131r. Aktif bile\u015feni mide asidine duyarl\u0131d\u0131r, bu nedenle onu korumak ve optimal emilim i\u00e7in ba\u011f\u0131rsaklarda serbest b\u0131rak\u0131lmas\u0131n\u0131 sa\u011flamak i\u00e7in enterik kaplama esast\u0131r.<\/p>\n<p>&nbsp;<\/p>\n<h2><span class=\"ez-toc-section\" id=\"2_Why_Enteric_Coating_Matters\"><\/span><strong><b>2. Enterik kaplama neden \u00f6nemlidir?<\/b><\/strong><span class=\"ez-toc-section-end\"><\/span><\/h2>\n<p>Enterik kaplama \u00fc\u00e7 kritik fonksiyona hizmet eder:<\/p>\n<p>\u0130la\u00e7 Koruma: Epalrestat'\u0131 gastrik asitten koruyarak etkinli\u011fini korur.<\/p>\n<p>Azalt\u0131lm\u0131\u015f tahri\u015f: mide astar\u0131 ile do\u011frudan temas\u0131 \u00f6nler.<\/p>\n<p>Hedeflenen Serbest B\u0131rakma: \u0130lac\u0131n yaln\u0131zca ba\u011f\u0131rsaklar\u0131n n\u00f6tr\/alkalin ortam\u0131nda \u00e7\u00f6z\u00fclmesini sa\u011flar.<\/p>\n<p>&nbsp;<\/p>\n<h2><span class=\"ez-toc-section\" id=\"3_The_Coating_Process\"><\/span><strong><b>3. Kaplama i\u015flemi<\/b><\/strong><span class=\"ez-toc-section-end\"><\/span><\/h2>\n<p><strong><b>3.1 Kaplamadan \u00f6nce haz\u0131rl\u0131k<\/b><\/strong><\/p>\n<table>\n<tbody>\n<tr>\n<td>Haz\u0131rl\u0131k \u00f6\u011fesi<\/td>\n<td>\u00d6zel Gereksinimler<\/td>\n<\/tr>\n<tr>\n<td>Ekipman kontrol\u00fc<\/td>\n<td>\u0130nceleyin\u00a0<a href=\"https:\/\/www.jianpaitech.com\/tr\/product_category\/coating-equipment\/\" target=\"_blank\" rel=\"noopener\"><em><strong>Kaplama ekipman\u0131<\/strong><\/em><\/a>\u00a0(\u00f6r. Jianpai\u2019nin makinesi) t\u00fcm par\u00e7alar\u0131n temiz ve i\u015flevsel olmas\u0131n\u0131 sa\u011flamak i\u00e7in.<\/td>\n<\/tr>\n<tr>\n<td>Malzeme ve Tablet Haz\u0131rl\u0131\u011f\u0131<\/td>\n<td>-Kaplama Malzemeleri: Asit diren\u00e7li, enterik polimerleri se\u00e7in.-Tabletler: Kusurlar\u0131 \u00e7\u0131karmak ve 2-3% nemine kurutmak i\u00e7in ekran \u00f6ncesi \u00e7ekirdekler.<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n<p>&nbsp;<\/p>\n<p><strong><b>3.2 Kaplama i\u015flemindeki temel ad\u0131mlar<\/b><\/strong><\/p>\n<p>Kaplama Malzemesi Haz\u0131rl\u0131\u011f\u0131: Enterik polimer, plastikle\u015ftirici ve renklendirici (gerekirse) 10-15% \u00e7\u00f6zeltisi olu\u015fturmak i\u00e7in safla\u015ft\u0131r\u0131lm\u0131\u015f su ile kar\u0131\u015ft\u0131r\u0131n.<\/p>\n<p>Ger\u00e7ek Kaplama \u0130\u015flemi:<\/p>\n<p>\u00c7ekirdek tabletleri d\u00f6nen tambura (10-15 rpm) y\u00fckleyin.<\/p>\n<p>P\u00fcsk\u00fcrtme tabancas\u0131n\u0131 (tablet yata\u011f\u0131ndan 15-20 cm) ayarlay\u0131n ve 5-10 ml\/dakikada p\u00fcsk\u00fcrt\u00fcn.<\/p>\n<p>Ger\u00e7ek zamanl\u0131 kurutma i\u00e7in davul s\u0131cakl\u0131\u011f\u0131n\u0131 40-45 \u00b0 C'de tutun.<\/p>\n<p>Kaplama istenen kal\u0131nl\u0131\u011fa ula\u015fana kadar tekrarlay\u0131n (5-10% a\u011f\u0131rl\u0131k art\u0131\u015f\u0131).<\/p>\n<p><a href=\"https:\/\/www.jianpaitech.com\/tr\/product\/model-jlb-series-fuild-bed-granulating-coating-machine\/\" target=\"_blank\" rel=\"noopener\"><img fetchpriority=\"high\" decoding=\"async\" class=\"alignleft wp-image-3277 size-full\" src=\"https:\/\/i1.wp.com\/www.jianpaitech.com\/wp-content\/uploads\/2025\/05\/Model-JLB-Series-Fuild-bed-Granulating-Coating-Machine-1.png?quality=85&strip=all\" alt=\"Model JLB Serisi S\u0131v\u0131 Yatan Gran\u00fclasyon Kaplama Makinesi\" width=\"750\" height=\"750\" srcset=\"https:\/\/i1.wp.com\/www.jianpaitech.com\/wp-content\/uploads\/2025\/05\/Model-JLB-Series-Fuild-bed-Granulating-Coating-Machine-1.png?quality=85&strip=all 750w, https:\/\/i1.wp.com\/www.jianpaitech.com\/wp-content\/uploads\/2025\/05\/Model-JLB-Series-Fuild-bed-Granulating-Coating-Machine-1-300x300.png?quality=85&strip=all 300w, https:\/\/i1.wp.com\/www.jianpaitech.com\/wp-content\/uploads\/2025\/05\/Model-JLB-Series-Fuild-bed-Granulating-Coating-Machine-1-150x150.png?quality=85&strip=all 150w\" sizes=\"(max-width: 750px) 100vw, 750px\" \/><\/a><\/p>\n<h2><span class=\"ez-toc-section\" id=\"4_Why_Jianpais_Coating_Machine_Stands_Out\"><\/span><strong><b>4. Jianpai\u2019nin Kaplama Makinesi Neden \u00d6ne \u00c7\u0131k\u0131yor?<\/b><\/strong><span class=\"ez-toc-section-end\"><\/span><\/h2>\n<p>Jianpai\u2019nin y\u00fcksek verimli <a href=\"https:\/\/www.jianpaitech.com\/tr\/product_category\/coating-equipment\/\" target=\"_blank\" rel=\"noopener\"><em><strong>kaplama makinesi<\/strong><\/em><\/a> \u00d6nemli avantajlar sunar:<\/p>\n<table>\n<tbody>\n<tr>\n<td>Avantaj<\/td>\n<td>Tan\u0131m<\/td>\n<\/tr>\n<tr>\n<td>\u00dcst\u00fcn s\u0131zd\u0131rmazl\u0131k<\/td>\n<td>\u00c7ift katmanl\u0131 bir silikon conta, \u00e7\u00f6zelti s\u0131z\u0131nt\u0131s\u0131n\u0131 ve kontaminasyonu \u00f6nler.<\/td>\n<\/tr>\n<tr>\n<td>Geli\u015fmi\u015f p\u00fcsk\u00fcrtme tabancas\u0131<\/td>\n<td>P\u00fcr\u00fczs\u00fcz, tek tip bir kaplama i\u00e7in t\u0131kanma \u00f6nleyici ve anti-da\u011f\u0131t\u0131c\u0131 tasar\u0131ma sahiptir.<\/td>\n<\/tr>\n<tr>\n<td>Ak\u0131ll\u0131 operasyon<\/td>\n<td>Dinamik parametre ekran ve i\u015flem veri depolama ile dokunmatik ekran kontrol\u00fc.<\/td>\n<\/tr>\n<tr>\n<td>Enerji tasarrufu tasar\u0131m\u0131<\/td>\n<td>De\u011fi\u015fken frekans pompas\u0131 ve ayarlanabilir egzoz, kaliteyi sa\u011flarken enerjiyi tasarruf edin.<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n<p>&nbsp;<\/p>\n<p>Sonu\u00e7lar ve video ekran\u0131<\/p>\n<p>Kullanma <a href=\"https:\/\/www.jianpaitech.com\/tr\/product_category\/coating-equipment\/\" target=\"_blank\" rel=\"noopener\"><em><strong>Jianpai\u2019nin Kaplama Makinesi<\/strong><\/em><\/a> M\u00fckemmel sonu\u00e7lar \u00fcretti:<\/p>\n<p>A\u011f\u0131rl\u0131k 10% artt\u0131 (kaplama standartlar\u0131n\u0131 kar\u015f\u0131l\u0131yor).<\/p>\n<p>Zarar oran\u0131 5% azald\u0131, sekt\u00f6r ortalamas\u0131ndan \u00f6nemli \u00f6l\u00e7\u00fcde daha d\u00fc\u015f\u00fck.<\/p>\n<p>Bu t\u00fcr tabletlerin m\u00fckemmel kaplamas\u0131n\u0131 g\u00f6rmek i\u00e7in l\u00fctfen videomuzu izleyin.<a href=\"https:\/\/www.jianpaitech.com\/tr\/product_category\/coating-equipment\/\" target=\"_blank\" rel=\"noopener\"> <em><strong>Jianpai\u2019nin Y\u00fcksek Verimli Kaplama Makinesi<\/strong><\/em><\/a>. Enterik kapl\u0131 epalrestat tabletleri tamamland\u0131. A\u011f\u0131rl\u0131k 10% artt\u0131 ve kay\u0131p 5% azald\u0131.<\/p>\n<p>&nbsp;<\/p>\n<p>&nbsp;<\/p>\n<h1><span class=\"ez-toc-section\" id=\"5_Conclusion\"><\/span><strong><b>5. Sonu\u00e7<\/b><\/strong><span class=\"ez-toc-section-end\"><\/span><\/h1>\n<p>Enterik tabletlerin kaplamas\u0131 ekipman, malzeme ve parametrelerin hassas kontrol\u00fcn\u00fc gerektirir.<a href=\"https:\/\/www.jianpaitech.com\/tr\/product_category\/coating-equipment\/\" target=\"_blank\" rel=\"noopener\"><em><strong> Jianpai\u2019nin Kaplama Ekipman\u0131<\/strong><\/em><\/a>\u00a0Bu s\u00fcreci basitle\u015ftirerek \u00fcr\u00fcn kalitesini ve \u00fcretim verimlili\u011fini art\u0131r\u0131rken acemi i\u00e7in uygun hale getirir.<\/p>\n<p>&nbsp;<\/p>\n<p>&nbsp;<\/p>","protected":false},"excerpt":{"rendered":"<p>Epalrestat, diyabetik n\u00f6ropatiyi tedavi etmek i\u00e7in \u00f6nemli bir ila\u00e7t\u0131r. Aktif bile\u015feni mide asidine duyarl\u0131d\u0131r, bu nedenle onu korumak ve optimal emilim i\u00e7in ba\u011f\u0131rsaklarda serbest b\u0131rak\u0131lmas\u0131n\u0131 sa\u011flamak i\u00e7in enterik kaplama esast\u0131r.<\/p>","protected":false},"featured_media":3278,"template":"","meta":{"_acf_changed":false,"footnotes":""},"blog_category":[16],"class_list":["post-4539","blog","type-blog","status-publish","has-post-thumbnail","hentry","blog_category-industry-news"],"acf":[],"_links":{"self":[{"href":"https:\/\/www.jianpaitech.com\/tr\/wp-json\/wp\/v2\/blog\/4539","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.jianpaitech.com\/tr\/wp-json\/wp\/v2\/blog"}],"about":[{"href":"https:\/\/www.jianpaitech.com\/tr\/wp-json\/wp\/v2\/types\/blog"}],"version-history":[{"count":5,"href":"https:\/\/www.jianpaitech.com\/tr\/wp-json\/wp\/v2\/blog\/4539\/revisions"}],"predecessor-version":[{"id":4545,"href":"https:\/\/www.jianpaitech.com\/tr\/wp-json\/wp\/v2\/blog\/4539\/revisions\/4545"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/www.jianpaitech.com\/tr\/wp-json\/wp\/v2\/media\/3278"}],"wp:attachment":[{"href":"https:\/\/www.jianpaitech.com\/tr\/wp-json\/wp\/v2\/media?parent=4539"}],"wp:term":[{"taxonomy":"blog_category","embeddable":true,"href":"https:\/\/www.jianpaitech.com\/tr\/wp-json\/wp\/v2\/blog_category?post=4539"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}